The plotline goes something like this. A good-hearted but bumbling security guard at the Museum of Natural History accidentally trips an ancient curse which causes the animals and gigantic insects on display to come to life, causing havoc in the city.
It is a very good family comedy and my family enjoyed it more than I thought we would. It's rated PG so there was not any crude/sexual humor like in some of Stiller's other movies. However, that did not take away from the humour at all. The best indicator of the success of any kid's film are the kids themselves and on this account, it was a resounding success! Not only did my own kids enjoy the movie immensely, the theater itself was jam packed with excited kids who shrieked joyously throughout the film!
Since the movie is now out in dollar theaters everywhere, its definitely worth the effort and outing to watch it as a family! You can check the timings and such using the Yahoo Movie page.